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These include metformin, sulfonylureas, meglitinides, thiazolidinediones, and insulin

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Applications of nano/micromotors for treatment and diagnosis in biological lumens

If the initial dosage proves insufficient or adverse effects are prominent, healthcare professionals may choose to titrate the dosage following the template's recommendations

In addition, the presence of immunosuppressive cytokines, such as transforming growth factor- (TGF-) and IL-10, contribute to the resistance of prostate cancer to immune checkpoint inhibitors by constructing an immunosuppressive tumor microenvironment and inhibiting the function of effector T cells (49)