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The Concept of Microdosing On social media and in some health circles, you may hear about microdosing or using smaller, more frequent dosesor larger, less frequent onesto find a sweet spot. While some individuals report success with this, it is not currently the FDA-recommended way to use these medications
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Blind cage coding and automated video analysis (EthoVision, TopScan) are recommended Too low n : prior power analysis, n 8 minimum for rodent behavioural tests No positive control : without memantine, donepezil or scopolamine depending on the paradigm, impossible to judge if the model is functional No dose-response : a single tested dose is insufficient to conclude
