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For many, the benefits of the medication outweigh this potential, though still uncertain, risk

For heart failure or chronic kidney disease, the American Diabetes Association generally recommends SGLT2 inhibitors as first-line agents, with GLP-1 receptor agonists considered for their benefits on atherosclerotic cardiovascular disease, glycemic control, and weight management, or when SGLT2 inhibitors are not appropriate

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Others may be curious because of cost considerations, access limitations, or a preference for gradual changes rather than rapid shifts in appetite or digestion

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