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placebo (800 mg of brown rice per day) for 4 months In the brown rice group, fibroid volume increased (24.3%) In the EGCG group, there was a significant decrease in the total uterine fibroid volume and a significant reduction in fibroid-specific symptom severity (32.4%) and a significant improvement in health-related quality of life compared to placebo

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Importantly, either genetic silencing of NCOA4 or treatment with the iron chelator deferoxamine (DFO) significantly attenuated these pathological changes, resulting in over 60% improvement in neuronal survival (Plascencia-Villa and Perry, 2021)

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