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The complex travels through the small intestine until it reaches the terminal ileum, where specialised receptors called cubam (a complex of cubilin and amnionless proteins) recognise and facilitate the uptake of the B12-IF complex into enterocytes (intestinal cells)

Biotin injection is used to treat or prevent biotin deficiency, a rare condition that can cause symptoms like hair loss, skin rashes, and brittle nails

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van Campen CLM, Riepma K, Visser FC

Phenytoin should be stopped if a drug rash appears