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-synuclein degradation assay To monitor the degradation capacity of the different 20S proteasomes, 1 pmol of the different proteasomes were incubated with 25 pmol of -synuclein a final volume of 56 l, in 50 mM HEPES buffer, pH 7.5, at 37 C

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Instead, by supporting GI tract integrity, it may help reduce one of the upstream drivers of autoimmune activation