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The Glu linker exits the receptor TM bundle between H296 ECL2 and W361 6.58 and the following short acyl segment merges into the detergent micelle, adjacent to a conserved lipid density (Fig

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Thus, the magnitude of serotonin amplification of ADP-induced platelet aggregation and dense granule secretion (DGS) may provide us with an index to evaluate the platelet serotonin responsivity

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