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doi:10.1038/s41598-017-01305-2

It works by mimicking the action of endogenous GLP-1, a hormone that stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and promotes satiety through central nervous system pathways

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GLP-1 (7-36) amide is secreted from the lower small intestine and shows a strong insulinotropic effect

Several factors either accelerate or slow the process

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