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Homocysteine, B vitamins, and cardiovascular disease: a Mendelian randomization study

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Because L-carnitine is known to be an essential co-factor in fatty acid and energy metabolism, and patients on dialysis tend to be malnourished, it might follow that repletion of L-carnitine by the intravenous or oral route could improve nutritional status, particularly among patients with low dietary L-carnitine intakes

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This includes mental clarity and general health in addition to physical attributes like vigor and strength