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GLP-1 receptors

The semaglutide group were significantly less likely to experience MACE

Patients were included if they had baseline bilateral pain radiographs demonstrating Kellgren and Lawrence grades of 1 to 3, as well as at least 2 years of follow-up before the initiation of GLP-1RA therapy for the sake of comparisons between groups

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Despite the limitations of real-world observational studiesincluding the absence of randomization, control for confounding variables, and inability to establish causalityresearches offer confidence regarding the pancreatic safety profiles of GLP-1 RAs [55,61]

Results May Vary: Individual results will vary based on factors including age, baseline condition, lifestyle factors, dietary habits, physical activity levels, consistency of use, genetic factors, current medications, and other individual variables