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Whats Coming: The BALANCE Model (May 2026) The biggest development in Medicaid GLP-1 coverage is the BALANCE Model (Better Approaches to Lifestyle and Nutrition for Comprehensive hEalth), announced by CMS in December 2025

Non-HDL cholesterol, LDL cholesterol, and serum uric acid all improved

Orforglipron for weight loss, a next-generation oral GLP-1 from Eli Lilly, is also progressing through trials and may offer additional options in the future

ITT, Insulin tolerance test

Consider eating water-rich foods, like cucumbers, watermelon, celery, and soup

Future Outlook and Approval Timeline Frequently Asked Questions Glossary of Terms References What Is Retatrutide and How Does It Work