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Based on clinical trial data, retatrutide produces greater average weight loss (28.7% at 68 weeks with 12mg) compared to tirzepatide (22.5% at 72 weeks with 15mg)

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Berberine also supports gut health by promoting beneficial bacteria and reducing inflammation, which can indirectly aid metabolism and weight management [1]

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Suspected adverse effects should be reported via the MHRA Yellow Card Scheme

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