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Early phase 2 clinical trials have reported weight reductions of 2030% of body weight at higher mg doses, figures that, if validated in larger trials, would represent a clinically significant advance over current options

Sheela Magge, director of pediatric endocrinology at Johns Hopkins Medicine in Baltimore, has seen an increase in cases of more severe obesity-related conditions in children, including non-alcoholic fatty liver disease

10.1097/HC9.0000000000000627

The semaglutide schedule starts at 0.25 mg weekly for four weeks and reaches the 2.4 mg maintenance dose after 16 weeks

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