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Evaluation of eryptosis has also been shown as a strategy to reveal sub-hemolytic cytotoxic effects against erythrocytes during development of nanomaterials-based drugs [220]

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For instance, certain studies have indicated that glutathione levels are lower in individuals with chronic kidney disease, highlighting its potential importance in renal health

At the moment, only two RCD modalities with clearly described and distinct molecularly defined pathways have been reported for mature erythrocytes, termed eryptosis and erythronecroptosis: counterparts of apoptosis and necroptosis (Fig