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Heart problems, including signs of rapid weight gain, general swelling or feeling like you're short of breath

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Increases in calcitonin levels have been observed in some patients, though the clinical significance remains uncertain

Consistently using the same spot can lead to skin irritation, scarring, or hard lumps under the skin

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In other words, vitamin B12 may be important for cellular immunity, especially for CD8 + cells and the NK cell system [50]