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It supports a wide array of body functions

When managing patients taking opioid analgesics, particularly those who have been treated for an extended period of time, and/or with high doses for chronic pain, ensure that a multimodal approach to pain management, including mental health support (if needed), is in place prior to initiating an opioid analgesic taper

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Although higher oxidative stress and an upregulation of amyloid (A) peptides from an extra copy of the APP gene are attributed to the AD susceptibility, the relationship between the two factors is unclear

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