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Public RNA-seq and proteomic datasets for FunMap analyses External datasets included BeatAML (707 samples), TCGA-AML (173 samples, cBioPortal), TARGET-AML (2,762 AML, 442 normal, 18 cell lines, GDC), Clinseq-AML (274 participants, Wang et al.), Blood2022 proteomics (44 participants, Kramer et al.) and DepMap 22Q2 cell line RNA-seq

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During HCV infection, for instance, in the acute phase, the activation of the Nrf2 pathway defends infected cells from inflammatory response, while during the chronic phase its inhibition restores the oxidative imbalance, thus favouring the virus persistence [140]

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