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90,91 Moreover, epidemiologic studies of different institutions showed that individuals with regular exercise, healthy diet (including more soluble fiber, colorful fruit, vegetables, green tea, or less intake of added sugars, carbs, trans-fats), limiting alcohol intake, avoiding smoking cigarettes and reduced levels of stress, which indeed increase insulin sensitivity

Sci Total Environ 476477:757767

The primary endpoint was NOT met

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Table 2 summarizes the current therapeutic approaches for mitigating iron overload and mitochondrial DNA mutations