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Studies are small, short-duration, and often poorly controlled

Lancet 397(10278):971984 Shi I, Khan SS, Yeh RW, Ho JE, Dahabreh IJ, Kazi DS (2025) Semaglutide Eligibility Across All Current Indications for US Adults

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In the present study, we did not, however, measure oxidative stress substrate markers, such as F2-isoprostanes, 8-OHdG, or malondialdehyde