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Activation of the HPA axis during the training greatly increases the cortisol levels (112), which acts as a metabolic and catabolic hormone (113) by mobilizing the glucose (114), endogenous stores of amino acids (115), and fatty acids (116), enhances the availability of all fuel substrates

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The findings of no increased heart rate in the setting of BP reduction may be interpreted as a result of relative reduction in the sympathetic nervous system tone, although modulation of other neurohormonal factors also could play a role (56)

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