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A preliminary 31P MRS study of autism: evidence for under synthesis and increased degradation of brain membranes

So maybe theyre getting a higher dose, Jay said

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118 Furthermore, cerebral hyperinsulinemia is associated with diminished clearance of A peptides due to the competitive inhibition of insulin-degrading enzyme, a metalloprotease responsible for degrading both insulin and A, which preferentially binds insulin over A under hyperinsulinemic conditions

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