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In this 40-week study, 1879 patients were randomly assigned, in a 1:1:1:1 ratio, to receive tirzepatide at a dose of 5 mg, 10 mg, or 15 mg or semaglutide at a dose of 1 mg per week

If you are shopping for a weekly weight-loss shot in Costa Rica, start with one fact that changes everything else: the drug most people are asking for by name is not legally sold here

The Transition: Your blood sugar levels begin to stabilize more consistently

Rizvi SM, Shakil S, Biswas D, et al

Carlat Verdict: To prevent metabolic side effects when beginning an antipsychotic, start with metformin, but consider a GLP-1 RA for patients who have already been on antipsychotics for a while with a BMI 30 kg/m 2 (or 27 kg/m 2 and obesity-related health problems)