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Lilly, Indianapolis, Indiana, USA), has sparked concerns about potential long-term safety risks

Analysis by the World Obesity Federation indicates that close to three billion people are affected by either overweight or obesity (NCD-RisC 2024)

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Semaglutide works by mimicking glucagon-like peptide-1 (GLP-1), a hormone that slows digestion and increases feelings of fullness, while metformin reduces glucose production in the liver and improves insulin sensitivity

Metabolic adaptation and appetite drift are listed as separate causes

Samir Rahmani assesses every patient across both pathways to recommend the most clinically appropriate and personally suitable treatment