J Pineal Res 36:155164 Leja-Szpak A, Jaworek J, Pierzchalski P, Reiter RJ (2010) Melatonin induces pro-apoptotic signaling pathway in human pancreatic carcinoma cells (PANC-1)
She et al., 2024) and blocks cortical neuronal oxidative damage by suppressing the p53-mediated Bcl-2/Bcl-2-associated X protein (Bax)/Caspase-3 apoptosis pathway and regulating the Kelch-like ECH-associated protein 1 (Keap1)/Nrf2 pathway, thus playing a pivotal role in reducing neuroinflammation (Yang C
This cytoskeletal stabilization is thought to contribute to its observed effects on tendon and ligament healing in animal models, where organized collagen deposition and tissue strength are paramount
Glutathione s-transferase When formed by oxidation of paracetamol, NAPQI is rapidly detoxified by conjugation with reduced GSH via reaction with GSHs sulfhydryl group
Anxiolytic-like effect of pyridoxine in mice by elevated plus maze and light and dark box: evidence for the involvement of GABAergic and NO-sGC-cGMP pathway
Surplus ROS attack DNA, inducing damage [107], and oxidize proteins, leading to protein misfolding and functional loss [108]
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