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Examination and initial investigations Recommended minimum evaluation for new or worsening vaginal symptoms in a semaglutide-treated patient generally mirrors standard care: External vulvar inspection for dermatoses (lichen sclerosus, eczema/contact dermatitis), fissures, atrophy signs

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doi: 10.1111/j.1600-0463.2011.02737.x 87 MengDCarvajalRD

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Studies using the GABA analog in Fmr1 knockout mice demonstrated corrections in hyperactivity and modulation of altered sensory-motor gating, measured as increased prepulse inhibition following acute treatment, by enhancing the activity of extrasynaptic GABA receptors, thereby improving anxiety, aggression, and repetitive behavioral abnormalities in FXS mice (71)

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