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Long-term safety of growth hormone therapy: still a controversial issue

Process of studies selection

Factors influencing variation in basal metabolic rate include fat-free mass, fat mass, age, and circulating thyroxine but not sex, circulating leptin, or triiodothyronine

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Basically, the LH contains two distinct neuronal cell populations that regulate feeding behaviour: containing hypocretin/orexin [57, 58] and a melanin-concentrating hormone (MCH) [59] (Figure 2)

As summarized in Fig