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"Recent trends in the metabolism and cell biology of vitamin K with special reference to vitamin K cycling and MK-4 biosynthesis"

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doi: 10.3390/antibiotics12071157 251 UthamanSKKangWSParkJYKimSLeDDOhSJet al

As shown in Figure 4A, cinchonine potentiated insulin secretion under high glucose conditions (11.1 and 16.7 mM) but had no effect under 2.8 mM glucose, which suggested that cinchonine induced insulin release in a glucose-dependent manner

The assessment should also explore realistic expectations, potential side effects, and the commitment required for successful treatment