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In children, hGH is officially authorized for therapy in the following indications: GHD Growth failure due to chronic renal insufficiency Noonan syndrome Prader-Willi syndrome Short bowel syndrome (SBS) Short stature homeobox (SHOX)-containing gene deficiency Small-for-gestational-age infants Turner syndrome In adults, hGH is also FDA-approved for therapy in: GHD SBS Muscle wasting due to AIDS Recombinant hGH therapy effectively increases serum growth hormone levels, addressing symptoms associated with GHD in both children and adults

Assessing genetic predispositions in peptide-related pathways supports more informed conversations with healthcare providers about both lifestyle interventions and medication candidacy

The amount of food intake was monitored at HFD period (16 weeks) to assess consumption and changes in body weight from baseline to post-intervention (HFD) was calculated

doi: 10.1200/JCO.2018.36.15_suppl.9528 180 SiLShengXMaoLLiCWangXBaiXet al

It is advisable to consult a healthcare professional before starting any new supplement regimen