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Notably, the treatment of animals with mitochondrial antioxidants was able to effectively protect the diaphragm from muscle fiber atrophy and contractile dysfunction induced by mechanical ventilation, further confirming the critical role of ROS in mediating muscle atrophy (151)

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Other researchers also reported an increase in F2-IsoPs concentrations in the blood serum (78) and exhaled breath condensate of asthma patients (86)