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When side effects occur, they're typically mild and transient

However, any combination should be approached thoughtfully with consideration of individual factors

The molecule was first identified and studied by the Sikiric research group in Croatia starting in the early 1990s, and the bulk of the preclinical evidence base comes from more than three decades of rat and rodent studies showing consistent tissue-repair, anti-inflammatory, and gastroprotective effects

Meanwhile, changes in quality-of-life scores measured by the Short Form-36 (SF-36) physical and mental components were small and not clinically significant across groups [1]

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These tests indicate how well the B12 is used in the cells