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& Clements, J

This imbalance may lead to disruptions in glucose and lipid homeostasis, contributing to a range of metabolic diseases, including obesity

Besides the 10 thermostabilizing mutations that reported previously 26,27 , E387 7.42b D was introduced to mimic the identified interaction in the GCGR-NNC1702 complex structure 9

doi: 10.1186/1471-2202-13-33 145 GaberySSalinasCGPaulsenSJAhnfelt-RnneJAlanentaloTBaqueroAFet al