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Therefore, individuals on both thyroid medication and GLP-1s need their thyroid hormone levels monitored more frequently, as their dosage may need to be adjusted downward over time to avoid overtreatment

Current Canadian pricing for established GLP-1 medications remains substantial: Mounjaro: Approximately $300-400 monthly depending on dose Zepbound: Similar pricing structure to Mounjaro Ozempic: $200-300 monthly across different strengths Wegovy: $400-500 monthly for maintenance doses Regulatory Pathway in Canada For Pfizer's long-acting GLP-1 drug to reach Canadian patients, the company must complete clinical trials and submit a New Drug Submission to Health Canada

More recently, high-dose (2.4mg) Semaglutide has been studied in non-diabetic patients suffering from obesity

In November, the White House announced a multi-pronged strategy to implement Most Favored Nation (MFN) pricing for GLP-1 drugs, which are increasingly prescribed for diabetes, obesity, and other indications