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Zepbound Starting at $299.00 1-month supply Zepbound (tirzepatide) is a once-weekly, FDA-approved GLP-1 medication used to manage weight gain

Cross-trial comparisons suggest retatrutide produces greater mean weight loss than semaglutide, though tolerability profiles are broadly similar

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We therefore propose that GLP-1RAs exert chondroprotective effects in RA, at least in part, by suppressing ferroptosis in chondrocytes mediated by cGASSTING pathway

2026;49(Suppl.1):S1-S5

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