A CoA is a document from an analytical laboratory confirming that a batch of active ingredient meets specifications
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Stability work on reconstituted somatropin at 1.0 and 3.33 mg/mL stored in polypropylene syringes confirmed maintained purity and potency for up to 28 days at 2-8 degrees C, with greater turbidity in alternative copolymer containers (Ray & Chen, 1998)
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Further evaluation indicated vitamin B12 deficiency and subsequently, pernicious anemia, as confirmed by low serum vitamin B12 levels and positive intrinsic cell antibody respectively
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