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At the 5mg/ml concentration, 100 units is straightforward but uses the entire syringe capacity
This could disrupt the current injectable-driven market
Obese patients are more likely to see knee arthritis due to stress on the joints caused by their weight, which leads to cartilage breakdown and inflammation
Week 1-4: 1mg weekly Week 5-8: 2mg weekly Week 9-12: 4mg weekly Week 13-16: 6mg weekly Week 17-20: 8mg weekly Week 21+: 12mg weekly (if tolerated) The Phase 3 TRIUMPH-4 trial used a slightly modified approach
Instead, they will start the medication from the starting dose and titrate it gradually
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