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CNS Neurosci Ther (2019) 25:46575

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This may be at room temperature [20-25C (68-77F)], refrigerated [2-8 C (36 -46 F)], or frozen [-15 to -25C (5 to -13F)]

Nrf2 is a transcription factor sequestered in the cytoplasm by its inhibitor protein, Keap1, under normal conditions (89)