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This suggests that ROS detoxification mediated by GpoA, as well as AhpD and TpxD, are important for the induction of antibiotic persistence under oxidative stress conditions, which is dependent of the imported glutathione (Fig

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A simplified explanation is that some of the homocysteine produced during methylation reactions is used to make cysteine, which is then combined with two other amino acids (glutamate and glycine) to form glutathione