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Using marker substrates to identify induction of specific P450s, Kreuger and coworkers provided a summary of sex and species differences in the magnitude of CYP enzyme induction

Although the final safety analysis is pending trial completion, the protocols rigorous adverse event monitoring represents a significant improvement over previous studies and will provide quantitative safety data essential for clinical translation (1)

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Dysregulation of secondary bile acid metabolism precedes islet autoimmunity and type 1 diabetes

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[DOI] [Google Scholar] 53.Garcia-Ruiz C., Morales A., Ballesta A., Rodes J., Kaplowitz N., Fernandez-Checa J.C