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A perda de GLP-1R em astrcitos pode prejudicar a captao de glicose e ativar respostas de estresse celular, demonstrando a importncia desse sistema para o equilbrio metablico cerebral

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Daily GIP injections led to a decrease in the adipose tissue gene expression levels of pro-inflammatory cytokines, such as Il-1 beta, Il-6, TNF-alpha in wild-type mice, 60 while blood levels of adiponectin, an anti-inflammatory and insulin-sensitizing adipokine, are enhanced