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Targeting CXCR1/2 in the first multicenter, double-blinded, randomized trial in autologous islet transplant recipients

Consume before, during, or after physical activity, or whenever additional hydration is needed

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doi: 10.3389/fnut.2022.1082097 Received 27 October 2022 Accepted 21 December 2022 Published 10 January 2023 Volume 9 - 2022 Edited by Sandro Massao Hirabara, Universidade Cruzeiro Do Sul, Brazil Reviewed by Elisabetta Camajani, Sapienza University of Rome, Italy

Abstract Providing NO-system importance, we suggest that one single application of the NOS-blocker L-NAME may induce retinal ischemia in rats, and that the stable pentadecapeptide BPC 157 may be the therapy, since it may interact with the NO-system and may counteract various adverse effects of L-NAME application