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[1] These medications include semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro, Zepbound)

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In the pancreas, activation stimulates glucose-dependent insulin secretion, meaning insulin is released only when blood glucose levels are elevated, which reduces the risk of hypoglycemia compared to some other diabetes medications

Studies tracking patients over 36 months show that bothersome side effects like vomiting or severe appetite loss affect fewer than 5% of people who complete the dose-escalation phase

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