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Inhibition of either PI3K or mTOR abolished accumulation of HIF-1 triggered by Exendin-4, suggesting that such event occurs downstream of mTOR (Fig

23 studies were excluded as they were post-mortem studies

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doi: 10.1186/s13073-021-00853-7

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Similar favorable results have also been reported in muscular dystrophy mice models, where sulforaphane treatment alleviated muscle inflammation in dystrophin-deficient mdx mice (Sun et al., 2015b)