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In particular, combining 2-OHNA with other NAD + biosynthesis inhibitors like FK866 effectively kills NAPRT-proficient cancer cells resistant to single-agent treatments 217

Similar to rapamycin 31 , these effects were achieved even though not initiated until later in life, which we reasoned to be a safer therapeutic window for IGF-1R modulation than younger ages 34

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Tell your provider if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath

& Kahn, M