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The addition of exogenous IGF-1 (50100 ng ml 1 ) caused a dose-dependent enhancement in the expression of the cytotoxic effector gene PRF1 , but no statistically significant differences could be detected for the mRNA levels of GzmB and IFNG in our experiments (Fig

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Immunostaining results showed an increase in Ki67 expression in the G/D-CuP group compared to other groups, while the control group exhibited minimal positive cells on day 7 (Fig

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