In the 1950s, bodybuilder and nutritionist Bob Hoffman revolutionized the industry with his chocolate-flavored Hi-Proteen supplements marketed to athletes, and in the 1970s, the weight-loss industry popularized protein shakes as meal replacements
What the trials established for the class The evidence base belongs to the compounds
Cardiovascular outcome trials (CVOTs) of GLP-1RAs To date, the REWIND study has demonstrated for the first time that primary cardiovascular prevention strategies can significantly reduce cardiovascular adverse events in patients with T2DM, regardless of whether or not these patients are co-diagnosed with CVD [23]
The app sets personalized targets based on your goals, though I found the calorie targets too low for very active people
Every participant in the 12mg group lost at least 5% of body weight
A phase 2 clinical trial published in JAMA (2023) reported significant reductions in body weight and improvements in metabolic markers
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