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[7] That preclinical promise carried the compound into a human Phase II program for postoperative ileus but the randomized, placebo-controlled trial in bowel-resection patients did not meet its primary efficacy endpoint, and clinical development was subsequently discontinued

doi:10.1016/j.nut.2020.111024

B12 shots have the potential for mild side effects, such as redness where the shot was injected or light diarrhea

The only way to know for sure if you need B12 injections is by getting a blood test

More than one in eight retatrutide-treated participants were completely pain-free at the end of the trial

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