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analyzed mutations in 232 genetically-profiled NSCLC patients and found that about half of the local recurrences, post-radiotherapy occurred in tumors with KEAP1/NFE2L2 mutations, indicating these mutations are major drivers of clinical radioresistance [25]

But compounded versions carry additional risks that patients need to understand

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The FDA warned that such compounds have not been assessed for efficacy or safety and carry risks

STEP 1, the pivotal registration trial, enrolled adults with a BMI of 30 kg/m (or 27 with comorbidities) without diabetes

doi:10.1016/j.fertnstert.2015.09.024