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8 An altered biochemistry in fibromyalgia is consistent with the decreased activity of the descending serotonergic-noradrenergic efferent pathways responsible for an aberrant diffuse noxious inhibitory control (DNIC)

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These combined effects can result in decreased blood glucose levels, very at higher doses or in fasted states

doi: 10.1046/j.1365-2826.2003.01092.x 10 BinaKGCincottaAH

The mechanism is similar to amphetamine, which is why the DEA classifies phentermine as a Schedule IV controlled substance