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The standard documented trial initiation dose is 0.3 mg once weekly, escalating over approximately 16 weeks toward higher investigational target doses, including the 2.4 mg/2.4 mg fixed-dose co-formulation regimen used in CagriSema studies [2]

Clinical trials show comparable weight loss magnitude (10.8% vs 12.9% at 26 weeks), but survodutide demonstrated 55% liver fat reduction in NASH patients

Hussain, I

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The compound has been around for half a century with a substantial global safety record