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doi: 10.1016/j.ctcp.2012.01.005

Additionally, even within the same category of GLP-1 mono-agonists or dual-agonists, there was considerable variability in weight reduction effects, which may be related to the different affinities of drugs for receptors [23,24]

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Vergs, B

The structural models of GHSR with the antagonist C12 and the neurotensin-NTSR-Gi complex used in this study are available in the Protein Data Bank database under accession codes 6KO5 and 6OS9

We may speculate that a larger reduction of plasma aldosterone in the patients with advanced CKD seen in our study could be caused by a higher local activity of RAAS due to kidney dysfunction